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The principle and metodical fundamentals of the method

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Mesodiencephalic modulation method (MDM) is based on the principle of influence of weak impulse currents of the frequency of about 10kHz on the mesodiencephalic area of the central nervous system. The effect is caused by electric impulses of current. DC modulated impulse electric currents in accordance with the ion and colloidal theory of internal environment cause electric polarization, which leads to rearrangement of ion structure, affection of cellular membranes function and have an activating effect on some structures and biological substrates of the cenral nervous system.

Physiological and therapeutic action of weak electric impulses on mesodiencephalic area

1. Bioelectrical action of weak electric impulses causes mainly the following changes:

a) at stress load, which is followed either by insufficient response or, vice versa, by exaggerated deleterious response from the cenral nervous system and mesodiencephalic area, due to influence of very weak impulse currents function of these parts of brain comes to normal, which results in enhancement of beta-endorphin contents, hypophysis axis action – adrenal gland with subsequent harmonization of ACTH secretion and thereby stimulation of adrenal cortex and release of steroid hormones. Furthermore, there occurs the release of somatotrophin into circulation, which results in modulation of the stress reaction process.

 

b) Decrease in functional hyperactivity of hypothalamus and mesodiencephalic area of brain, including reticular formation through action of weak impulse currents helps to regulate hyperactivity of the brain to external impetuses, has sedative effects and smothers emotional reactions to stress.

c) Action of weak impulse currents on mesodiencephalic area results in regulation of pain perception threshold, has analgesic effects and regulates hypersensibility caused by immoderate irritation of peripheral nerves of different etiology, particularly disorders of function of thick and thin nerve fibre of peripheral nerves.

 

Thereby difficulties caused by diabetic polyneuropathy of symmetrical and focal types are significantly ameliorated and eliminated.

2. Influence on the secretion of ACTH and steroid hormones results in the regulation of insufficient or excessive secretion of steroid hormones and thereby eliminates disorders caused by pathological reaction to allergens.


Mesodiencephalic modulation method

– the principle and application of the method -

General indications of MDM

1. Electroanalgesia in disorders of peripheral nerves, particularly in diabetic polyneuropathy.

2. Modulation of the reaction to the stress from the excessive irritation of mesodiencephalic structures.

3. Favourable influence on the central and peripheral microcirculation.

 

General contraindications

1. Diseases of haematogenesis, disorders of fluido-coagulation balance.

2. Serious disorders of cardiac rate (bradycardia, ventricular arrhythmia).

3. Malignant tumors.

4. Benign tumors which tend to grow quickly.

5. Presence of metallic objects in the cranial cavity.

6. Epilepsy.

7. Psychoses, schizophrenia.

 

Conclusion

Mesodiencephalic modulation method is a physical way of treatment, which regulates functional disorders caused by the dysregulation in chronic disorders occurring when there is the damage to peripheral nervous system, particularly in diabetic polyneuropathy. It is a completely safe method, which may be used separately and in combination with pharmacotherapy as a suitable complement. Alongside with the treatment of diabetic polyneuropathy, which was clinically examined and evaluated with a very positive result, the method is applicable for other types of polyneuropathy, which are difficultly accessible to pharmacological treatment.

Prof.MUDr.Zdenek Zadak, CSc.

Teaching Hospital in Hradec Kralove